As decisions about organ allocation are made, they should be informed by outcomes data after LT. These developments will compound the relative shortage of donated organs and raise concern about the benefits of LT for older recipients. 2 Consequently, more elderly patients with liver failure might be considered candidates for LT. More people will reach older age in better health than in previous generations. In addition, the relative percentage of people in older age groups is increasing more rapidly than that of the other groups in the population by the year 2030, the percentage of the population aged 75 years and older is estimated to increase from 6% to 9% and will continue to increase to 12% by 2050. 1 This success has expanded the pool of transplant recipients to include persons previously considered ineligible because of advanced age and comorbid conditions. Improved patient and allograft survival after liver transplant (LT) reflects advances in surgical techniques, anesthesia, critical care, and infection control, as well as the development of targeted, potent immunosuppressants. The frequency of other complications did not differ significantly between age groups, although older patients had more cardiovascular complications.ĬONCLUSION: Five-year mortality and graft loss in older recipients were comparable with those in younger recipients, suggesting that age alone should not exclude older patients from liver transplant.ĬI = confidence interval LT = liver transplant MELD = model for end-stage liver disease RR = relative risk ![]() ![]() OBJECTIVE: To compare mortality, graft loss, and postoperative complications after liver transplant in older patients (≥70 years) with those in younger patients (.99) or graft loss (relative risk, 1.17 95% confidence interval, 0.54-2.52 P=.70).
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